The appeal is also likely to feature previously unseen footage of Madeleine who was nearly four when she vanished from a holiday apartment in Portugal 19 months ago. The Find Madeleine Fund is to foot the cost of the new appeal.
The McCanns spokesman Clarence Mitchell confirmed that discussions were underway over the fresh appeal.
"It is likely there will be a Christmas message with the focus on Madeleine," he said.
Mr Mitchell would not comment on who had been approached to narrate the film, but it is believed to be a sporting hero or some other celebrity.
The message will be done in video format so it can be used by broadcasters and the Find Madeline Fund website.
It is believed the McCanns do not want to appear themselves but are keen to spark renewed interest in the search.
Last month the McCanns admitted they faced a new blow in their hunt for their daughter.
They said there was less information in the released Portuguese police files than they had hoped. Among the files was a prosecutor's report that said the investigation had uncovered "very little" conclusive about Madeleine's fate.
The McCanns also confessed to being "low" as the 18th month milestone of Madeleine's disappearance passed, but have expanded their support team to try and find their daughter and understand what has - and has not - been done by the Portuguese police.
The McCanns have already spent more than ?1m trying to find Madeleine, who disappeared on May 3, 2007 from the resort of Praia da Luz, in the Algarve region of Portugal, just days short of her fourth birthday.
The McCanns have previously accused the Poli?cia Judiciaria (PJ) - the Portuguese criminal investigation police - of exaggerating DNA evidence to name them as suspects after Madeleine vanished.
The police inquiry into the girl's disappearance was wound up in July due to a lack of evidence.
The McCanns and a third British national, Robert Murat - who have always strongly denied having had any involvement in what happened to Madeleine - were then declared to no longer be formal suspects.
The McCanns have vowed to "leave no stone unturned" in their hunt for Madeleine - who they firmly believe is still alive - and also say they may change the way they keep people updated about the hunt for their daughter.