The 4-year-old disappeared from her family's holiday apartment in Portugal on May 3.
And now, 100 days later, the search for Madeleine goes on.
Her parents, Kate and Gerry McCann are keen that people remain vigilent wherever they may be.
At Saturday's Premier League game against Wigan, Everton will be playing a special DVD message on the big screens at half time.
The players will be warming up in special t-shirts and the Toffee Lady will throw Find Madeleine wristbands into the crowd.
Mrs McCann said: "It doesn't get any easier. The 50th day seemed like such a long time when we marked that. We have doubled that now."
international number for
Crimestoppers is +44
1883 731 336. People
with information about
Madeleine can call