The 42-year-old spoke out as she and husband revealed that their multi-million pound appeal fund will run dry within months.

Kate McCann accused the Government of giving up the hunt for the child who went missing shortly before her fourth birthday. She said a series of ministers had shrugged off her pleas for help.

Tireless: Kate and Gerry McCann have warned the fund to find their missing daughter will run out of money

‘I don’t want to be appeased, and that’s what I feel we’re getting. We need action, I don’t need fluffy worthless words,’ she said.

The couple have written an open letter, begging for political and financial help and launched an online petition to lobby the British and Portuguese governments for a formal review of the case. 

Mr McCann said: ‘We have tried in vain to get the authorities to play their part but our requests have seemingly fallen on deaf ears.’

Madeleine vanished in 2007 during a family holiday in the Algarve resort of Praia da Luz.

Huge effort: Madeleine McCann went missing in May 2007

Portuguese police shelved an 18-month investigation into the disappearance after clearing her parents as formal suspects, and the case has remained closed.

Mr and Mrs McCann, of Rothley, Leicestershire, have met a series of ministers in the hope that the case will be re-opened or a cold-case review of the investigation launched.

Their hopes were raised when the Labour government looked at the feasibility of an Interpol review of the disappearance.

But when they met Home Secretary Theresa May in August, they learned the new Home Secretary had not read the report.

The McCanns have used £2million in public donations to pay for private detectives.

But heart consultant Mr McCann, also 42, said the fund would run dry early next year, and begged for donations.

Mrs McCann said: ‘We can’t stop trying to find Madeleine – or at the very least find out what’s happened.’

The Home Office said: ‘The Government wants to ensure that everything feasible is being done to progress the search.